Pepperoni Pizza Casserole


Craving the comforting flavors of pizza but want a simpler, fuss-free option? Look no further than Pepperoni Pizza Casserole! This hearty dish takes all the delicious elements of a classic pizza and transforms them into a satisfying casserole that’s perfect for feeding a crowd or enjoying as a cozy family dinner. In this article, we’ll delve into what makes Pepperoni Pizza Casserole so irresistible and provide you with an easy-to-follow recipe that’s sure to become a favorite in your household.


  •  8 oz rotini pasta, cooked and drained
  •  1 lb ground beef
  •  1 cup pepperoni slices
  •  1 cup shredded mozzarella cheese
  •  1 cup shredded cheddar cheese
  •  1 can pizza sauce
  •  1 teaspoon Italian seasoning
  •  Salt and pepper to taste


  1. Preheat the oven to 375F 190C.
  2. In a skillet, I brown the ground beef and season it with salt and pepper.
  3. In a large bowl, I combine the cooked pasta, browned beef, pepperoni slices, mozzarella cheese, cheddar cheese, pizza sauce, and Italian seasoning.
  4. I transfer the mixture to a greased baking dish.
  5. I bake it for 25-30 minutes or until it becomes bubbly and golden.
  6. I allow it to cool for a few minutes before serving.


  1.  Personalize with your preferred pizza toppings.
  2.  Enhance with a layer of sliced bell peppers or olives for added veggies.
  3.  Sprinkle grated Parmesan on top before baking for a cheesy crust.

Serving Tips:

  1. Allow the Pepperoni Pizza Casserole to cool for a few minutes after removing it from the oven to prevent burns and ensure easier slicing.
  2. Garnish the casserole with fresh herbs, such as chopped basil or parsley, for a pop of color and added flavor.
  3. Serve the casserole alongside a crisp green salad or steamed vegetables for a balanced meal.
  4. For a festive touch, sprinkle some extra grated Parmesan cheese or red pepper flakes over the top of the casserole just before serving.
  5. If serving at a party or gathering, consider cutting the casserole into smaller squares for easy, grab-and-go portions.

Storage Tips:

  1. Allow any leftovers to cool completely before storing them in an airtight container or wrapping them tightly with plastic wrap.
  2. Store the leftover Pepperoni Pizza Casserole in the refrigerator for up to 3-4 days.
  3. To reheat, place individual portions in the microwave for quick and convenient reheating, or reheat larger portions in the oven at 350°F (175°C) until heated through.
  4. Alternatively, you can freeze the Pepperoni Pizza Casserole for longer storage. Wrap individual portions or the entire casserole tightly in plastic wrap and aluminum foil before placing it in the freezer.
  5. The frozen casserole can be reheated directly from the freezer in the oven. Simply remove the plastic wrap and foil, cover the casserole with foil, and bake at 350°F (175°C) until heated through, adding a few extra minutes to the cooking time as needed.


1. Can I customize the toppings in Pepperoni Pizza Casserole? Yes, absolutely! Pepperoni Pizza Casserole is highly customizable. You can add your favorite pizza toppings such as bell peppers, onions, mushrooms, olives, or even cooked sausage or bacon to tailor the casserole to your taste preferences.

2. Can I make Pepperoni Pizza Casserole ahead of time? Yes! Pepperoni Pizza Casserole can be assembled ahead of time and stored in the refrigerator until ready to bake. Simply cover the assembled casserole dish with plastic wrap or aluminum foil and refrigerate for up to 24 hours before baking as directed.

3. Can I use a different type of pasta in this recipe? While rotini pasta works well in Pepperoni Pizza Casserole due to its spiral shape that holds the sauce and toppings, you can certainly experiment with other pasta shapes such as penne, rigatoni, or even spaghetti. Just be sure to adjust the cooking time according to the pasta’s package instructions.

4. Can I make Pepperoni Pizza Casserole without meat? Absolutely! If you prefer a vegetarian version of Pepperoni Pizza Casserole, simply omit the pepperoni or substitute it with your favorite vegetarian alternative, such as sliced mushrooms, diced bell peppers, or black olives. The casserole will still be delicious and satisfying.

5. How do I prevent the casserole from drying out when reheating leftovers? To prevent the casserole from drying out when reheating leftovers, consider adding a splash of marinara sauce or a drizzle of olive oil before reheating. Cover the dish with foil to help retain moisture, and heat it gently in the oven or microwave until warmed through. Alternatively, you can sprinkle a bit of water over the top of the casserole before reheating to add moisture.


Pepperoni Pizza Casserole offers all the irresistible flavors of pizza in a convenient casserole format that’s sure to satisfy even the pickiest eaters. With its quick and easy preparation and endless customization options, this dish is perfect for busy weeknights, casual gatherings, or cozy family dinners. So why wait? Gather your ingredients and whip up a batch of Pepperoni Pizza Casserole tonight for a deliciously satisfying meal that’s sure to please everyone at the table.