Cheesy Chicken Parmesan Casserole Recipe

If you’re craving a comforting, hearty dish that’s bursting with flavor and melts in your mouth, this Cheesy Chicken Parmesan Casserole Recipe is going to be your new go-to. I love how this casserole brings together tender chicken, gooey melted cheese, and a crispy breadcrumb topping all baked in a rich marinara sauce—it’s like all your favorite Italian flavors wrapped into one easy meal. Plus, it’s a perfect weeknight dinner when you want something satisfying but don’t want to fuss too much in the kitchen.

What makes this Cheesy Chicken Parmesan Casserole Recipe really stand out is how simple it is to throw together—with minimal hands-on time yet maximum comfort food vibes. The uncooked pasta cooks right in the sauce, soaking up all those savory juices, while the breadcrumb topping adds a lovely golden crunch. Trust me, once you try this, it’s going to become a staple for busy evenings, potlucks, or whenever you need a big, cozy dish to share.

Ingredients You’ll Need

Each ingredient in this recipe pairs beautifully to create that classic chicken Parmesan flavor in casserole form. I find using quality marinara and fresh garlic really elevates the dish, and the gluten-free options mean it’s friendly for many diets without sacrificing taste.

• Chicken: Bite-sized cubes work best to ensure the chicken cooks evenly and every bite has a bit of juicy meat.
• Gluten-free pasta penne or rotini: Penne or rotini helps hold the sauce well; I love Jovial brand for great texture.
• Cherry tomatoes: They burst with sweetness in the oven, balancing the savory sauce perfectly.
• Marinara sauce: About 40 oz gives the casserole that rich, classic Italian flavor—homemade or your favorite store brand works great.
• Chicken broth: Adds moisture and depth, keeping the pasta from drying out.
• Garlic cloves: Fresh minced garlic packs a punch that you really want in this dish.
• Butter: Used for melting into the breadcrumb topping to create that irresistible golden crust.
• Gluten-free breadcrumbs or crushed gluten-free crackers: Toasted with spices for a crunchy texture.
• Garlic powder, onion powder, Italian seasoning: Essential spices for that signature chicken Parmesan flavor.
• Salt and pepper: To taste, because seasoning is everything.
• Grated Parmesan cheese: Optional, but I always add it fresh on top for that tangy, salty touch.
• Shredded mozzarella cheese: The ooey-gooey heart of the dish; dairy-free options work well, too.
• Fresh basil: Garnish to add a pop of herbal brightness and freshness.

Variations

I like to switch things up depending on what I have on hand or who I’m cooking for. This Cheesy Chicken Parmesan Casserole Recipe is super forgiving and invites your own twists, so don’t hesitate to experiment and make it your own.

• Use leftover rotisserie chicken: When I’m short on time, shredded rotisserie chicken is a lifesaver and still tastes amazing.
• Add veggies: Mushrooms, spinach, or bell peppers can sneak in extra nutrition and flavor without overpowering the dish.
• Spicy twist: Sprinkle some crushed red pepper flakes in if you enjoy a little heat.
• Dairy-free version: Swap mozzarella and Parmesan with your favorite plant-based cheeses; the casserole still melts beautifully.
• Cheese overload: For cheese lovers, mixing in some provolone or fontina adds even more richness.

How to Make Cheesy Chicken Parmesan Casserole Recipe

Step 1: Prep the base and get it baking

Start by preheating your oven to 400°F (204°C) and greasing a 9×13-inch baking dish. I like to use a little butter or olive oil spray so nothing sticks later. Next, toss together cubed chicken, uncooked gluten-free pasta, marinara sauce, chicken broth, cherry tomatoes, minced garlic, and your seasonings right in the dish. Stir gently to combine everything evenly. Cover with foil and pop it in the oven for 25 minutes—this allows the pasta to begin absorbing flavors and the chicken to start cooking.

Step 2: Make a golden breadcrumb topping

While the casserole bakes, melt 1 tablespoon of butter in a skillet over medium heat. Add gluten-free breadcrumbs, garlic powder, onion powder, Italian seasoning, and a pinch of salt. Keep stirring frequently to toast the crumbs until they’re golden brown and fragrant—this gives you that much-loved crispy texture on top. It’s such a simple step that really elevates the overall dish.

Step 3: Add cheese and finish baking

Remove the casserole from the oven and take off the foil. Sprinkle shredded mozzarella cheese evenly over the top, then layer on your toasted breadcrumb mixture. Pop it back in the oven uncovered for another 20-25 minutes. You’re aiming for bubbly, golden cheese and fully cooked chicken that hits 165°F internally. Keep an eye on it near the end so the topping doesn’t burn.

Step 4: Garnish and serve

Once out of the oven, let the casserole rest for a few minutes. If you want, sprinkle fresh Parmesan cheese and torn basil leaves on top. The fresh herbs add a lovely brightness that cuts through the richness and makes every bite taste fresh and homemade.

How to Serve Cheesy Chicken Parmesan Casserole Recipe

Garnishes

I always reach for fresh basil and a light dusting of Parmesan when serving this casserole. Sometimes I drizzle a little extra virgin olive oil on top for a silky finish, especially if the cheese looks a bit dry. Little details like that really make the dish shine and impress guests without extra work.

Side Dishes

For sides, I like to keep it simple so the casserole is the star. A crisp green salad with lemon vinaigrette or some roasted veggies like asparagus or broccoli pairs perfectly. Garlic bread or a simple gluten-free baguette also makes a nice complement for soaking up extra sauce.

Creative Ways to Present

For a dinner party, I’ve served this casserole in individual ramekins and topped each with a little basil leaf and a cherry tomato half for a pretty touch. You can also sprinkle some toasted pine nuts or fresh cracked black pepper for added texture and flavor contrast. It makes a hearty but elegant centerpiece!

Make Ahead and Storage

Storing Leftovers

Leftover cheesy chicken Parmesan casserole keeps beautifully in the fridge for 3-4 days. I like storing it in an airtight container so it doesn’t absorb other fridge odors. When you’re ready to eat, simply reheat and enjoy the flavors just like the first night.

Freezing

This casserole freezes well, which is great for batch cooking. I portion it into freezer-safe containers or freeze the whole pan if I’m prepping for the week. Just make sure it’s cooled completely before wrapping tightly to prevent freezer burn. When you thaw it overnight, it reheats just as nicely.

Reheating

The best way I’ve found to reheat this casserole is in the oven at 350°F, covered loosely with foil to keep moisture in. After about 20-25 minutes, remove the foil to crisp up the breadcrumb topping again if desired. Microwaving works in a pinch but the topping won’t stay crunchy.

FAQs

Final Thoughts

This Cheesy Chicken Parmesan Casserole Recipe holds a special place in my recipe box because it’s both comforting and surprisingly easy. I love how it brings layers of flavors and textures without requiring hours of prep or complicated steps. If you’re looking for a family-friendly, crowd-pleasing meal that warms you up from the inside out, you really can’t go wrong with this one. Give it a try—you’ll be amazed how something so comforting can come together so effortlessly.